A new study by Columbia University Medical Center, published in July's Journal of Clinical Investigation, suggests that obese participants who dieted down to lower weights experienced significant reductions in leptin. . . related to increased food intake. Implications for weight loss? When you diet, your body works overtime to help you re-gain the weight, explaining why over 95% of all diets fall.
The Columbia Medical Center Record quotes Dr. Rudolph Leibel, an investigator on the project:
Weight gain is unfortunately very common following otherwise successful weight reduction. . . . Brain images confirm that the body is subject to powerful biological forces that regulate food intake--forces that are beyond an individual's conscious control. Obese people who may have struggled to shed 20 pounds will have lower blood levels of leptin that will cause persistent hunger. Combined with reduced energy expenditure--also caused by lower leptin--that's the perfect storm for re-gaining the weight.